Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts.

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  • Additional Information
    • Author-Supplied Keywords:
      antimycotoxigenic activity
      Aspergillus flavus
      Citrullus colocynthis
      HPLC-MS/MS
      model system
    • Abstract:
      Citrullus colocynthis L. Schrader is an annual plant belonging to the Cucurbitaceae family, widely distributed in the desert areas of the Mediterranean basin. Many pharmacological properties (anti-inflammatory, anti-diabetic, analgesic, anti-epileptic) are ascribed to different organs of this plant; extracts and derivatives of C. colocynthis are used in folk Berber medicine for the treatment of numerous diseases—such as rheumatism arthritis, hypertension bronchitis, mastitis, and even cancer. Clinical studies aimed at confirming the chemical and biological bases of pharmacological activity assigned to many plant/herb extracts used in folk medicine often rely on results obtained from laboratory preliminary tests. We investigated the biological activity of some C. colocynthis stem, leaf, and root extracts on the mycotoxigenic and phytopathogenic fungus Aspergillus flavus, testing a possible correlation between the inhibitory effect on aflatoxin biosynthesis, the phytochemical composition of extracts, and their in vitro antioxidant capacities. [ABSTRACT FROM AUTHOR]
    • Abstract:
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    • Author Affiliations:
      1Department of Chemistry, Life Sciences and Environmental Sustainability, University of Parma, Parco Area delle Scienze 11/A, 43124 Parma, Italy
      2Center for Molecular and Translational Oncology, Parco Area delle Scienze, 43124 Parma, Italy
      3Department of Cell Biology, New York University Medical Center, New York, New York, U.S.A
    • ISSN:
      2072-6651
    • Accession Number:
      10.3390/toxins11050286
    • Accession Number:
      136711464
  • Citations
    • ABNT:
      DEGOLA, F. et al. Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts. Toxins, [s. l.], v. 11, n. 5, p. 286, 2019. DOI 10.3390/toxins11050286. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=136711464&custid=s8280428. Acesso em: 18 fev. 2020.
    • AMA:
      Degola F, Dramis L, Restivo FM, et al. Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts. Toxins. 2019;11(5):286. doi:10.3390/toxins11050286.
    • APA:
      Degola, F., Dramis, L., Restivo, F. M., Buschini, A., Marzouk, B., Gori, A., Brunetti, C., & Gelati, S. (2019). Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts. Toxins, 11(5), 286. https://doi.org/10.3390/toxins11050286
    • Chicago/Turabian: Author-Date:
      Degola, Francesca, Lucia Dramis, Francesco M. Restivo, Annamaria Buschini, Belsem Marzouk, Antonella Gori, Cecilia Brunetti, and Stefania Gelati. 2019. “Aspergillus Flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus Colocynthis L. Schrad. Organic Extracts.” Toxins 11 (5): 286. doi:10.3390/toxins11050286.
    • Harvard:
      Degola, F. et al. (2019) ‘Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts’, Toxins, 11(5), p. 286. doi: 10.3390/toxins11050286.
    • Harvard: Australian:
      Degola, F, Dramis, L, Restivo, FM, Buschini, A, Marzouk, B, Gori, A, Brunetti, C & Gelati, S 2019, ‘Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts’, Toxins, vol. 11, no. 5, p. 286, viewed 18 February 2020, .
    • MLA:
      Degola, Francesca, et al. “Aspergillus Flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus Colocynthis L. Schrad. Organic Extracts.” Toxins, vol. 11, no. 5, May 2019, p. 286. EBSCOhost, doi:10.3390/toxins11050286.
    • Chicago/Turabian: Humanities:
      Degola, Francesca, Lucia Dramis, Francesco M. Restivo, Annamaria Buschini, Belsem Marzouk, Antonella Gori, Cecilia Brunetti, and Stefania Gelati. “Aspergillus Flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus Colocynthis L. Schrad. Organic Extracts.” Toxins 11, no. 5 (May 2019): 286. doi:10.3390/toxins11050286.
    • Vancouver/ICMJE:
      Degola F, Dramis L, Restivo FM, Buschini A, Marzouk B, Gori A, et al. Aspergillus flavus as a Model System to Test the Biological Activity of Botanicals: An Example on Citrullus colocynthis L. Schrad. Organic Extracts. Toxins [Internet]. 2019 May [cited 2020 Feb 18];11(5):286. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=136711464&custid=s8280428