Clinical presentation and initial management of black men and white men with prostate cancer in the United Kingdom: the PROCESS cohort study.

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  • Additional Information
    • Subject Terms:
    • Author-Supplied Keywords:
      clinical management
      diagnosis
      epidemiology
      ethnicity
      prostate cancer
    • NAICS/Industry Codes:
      621494 Community health centres
      621498 All Other Outpatient Care Centers
      621499 All other out-patient care centres
      621110 Offices of physicians
    • Abstract:
      Background: In the United States, Black men have a higher risk of prostate cancer and worse survival than do White men, but it is unclear whether this is because of differences in diagnosis and management. We re-examined these differences in the United Kingdom, where health care is free and unlikely to vary by socioeconomic status.Methods: This study is a population-based retrospective cohort study of men diagnosed with prostate cancer with data on ethnicity, prognostic factors, and clinical care. A Delphi panel considered the appropriateness of investigations and treatments received.Results: At diagnosis, Black men had similar clinical stage and Gleason scores but higher age-adjusted prostate-specific antigen levels (geometric mean ratio 1.41, 95% confidence interval (95% CI): 1.15-1.73). Black men underwent more investigations and were more likely to undergo radical treatment, although this was largely explained by their younger age. Even after age adjustment, Black men were more likely to undergo a bone scan (odds ratio 1.37, 95% CI: 1.05-1.80). The Delphi analysis did not suggest differential management by ethnicity.Conclusions: This UK-based study comparing Black men with White men found no evidence of differences in disease characteristics at the time of prostate cancer diagnosis, nor of under-investigation or under-treatment in Black men. [ABSTRACT FROM AUTHOR]
    • Abstract:
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    • Author Affiliations:
      1Department of Social Medicine, University of Bristol, 39 Whatley Road, Bristol, BS8 2PS, UK
      2Department of Urology, University Hospitals Bristol NHS Foundation Trust, Bristol Royal Family, Upper Maudlin Street, Bristol, BS2 8HW, UK
      3Department of Urology and Pathology, St George's Hospital, Blackshaw Road, Tooting, London, SW17 0QT, UK
      4Department of Urology, Barts and the London NHS Trust, St Bartholomew's Hospital, West Smithfield, London, EC1A 7BE, UK
      5Department of Urology, Newham University Hospital NHS Trust, Glen Road, London, E13 8SL, UK
      6Department of Urology, North Bristol NHS Trust, Southmead Hospital, Southmead Road, Bristol, BS10 5NB, UK
      7Department of Urology, King's College Hospital NHS Trust, Denmark Hill, London, SE5 9RS, UK
      8Department of Urology, Guy's and St Thomas' NHS Foundation Trust, Guy's Hospital, Great Maze Pond, London, SE1 9RT, UK
      9Bristol Oncology Centre, Bristol Haematology and Oncology Centre, Horfield Road Bristol, Bristol, BS2 8ED, UK
    • ISSN:
      0007-0920
    • Accession Number:
      10.1038/sj.bjc.6605461
    • Accession Number:
      47602674
  • Citations
    • ABNT:
      EVANS, S. et al. Clinical presentation and initial management of black men and white men with prostate cancer in the United Kingdom: the PROCESS cohort study. British Journal of Cancer, [s. l.], v. 102, n. 2, p. 249–254, 2010. Disponível em: . Acesso em: 18 out. 2019.
    • AMA:
      Evans S, Metcalfe C, Patel B, et al. Clinical presentation and initial management of black men and white men with prostate cancer in the United Kingdom: the PROCESS cohort study. British Journal of Cancer. 2010;102(2):249-254. doi:10.1038/sj.bjc.6605461.
    • APA:
      Evans, S., Metcalfe, C., Patel, B., Ibrahim, F., Anson, K., Chinegwundoh, F., … Ben-Shlomo, Y. (2010). Clinical presentation and initial management of black men and white men with prostate cancer in the United Kingdom: the PROCESS cohort study. British Journal of Cancer, 102(2), 249–254. https://doi.org/10.1038/sj.bjc.6605461
    • Chicago/Turabian: Author-Date:
      Evans, S., C. Metcalfe, B. Patel, F. Ibrahim, K. Anson, F. Chinegwundoh, C. Corbishley, et al. 2010. “Clinical Presentation and Initial Management of Black Men and White Men with Prostate Cancer in the United Kingdom: The PROCESS Cohort Study.” British Journal of Cancer 102 (2): 249–54. doi:10.1038/sj.bjc.6605461.
    • Harvard:
      Evans, S. et al. (2010) ‘Clinical presentation and initial management of black men and white men with prostate cancer in the United Kingdom: the PROCESS cohort study’, British Journal of Cancer, 102(2), pp. 249–254. doi: 10.1038/sj.bjc.6605461.
    • Harvard: Australian:
      Evans, S, Metcalfe, C, Patel, B, Ibrahim, F, Anson, K, Chinegwundoh, F, Corbishley, C, Gillatt, D, Kirby, R, Muir, G, Nargund, V, Popert, R, Wilson, P, Persad, R & Ben-Shlomo, Y 2010, ‘Clinical presentation and initial management of black men and white men with prostate cancer in the United Kingdom: the PROCESS cohort study’, British Journal of Cancer, vol. 102, no. 2, pp. 249–254, viewed 18 October 2019, .
    • MLA:
      Evans, S., et al. “Clinical Presentation and Initial Management of Black Men and White Men with Prostate Cancer in the United Kingdom: The PROCESS Cohort Study.” British Journal of Cancer, vol. 102, no. 2, Jan. 2010, pp. 249–254. EBSCOhost, doi:10.1038/sj.bjc.6605461.
    • Chicago/Turabian: Humanities:
      Evans, S., C. Metcalfe, B. Patel, F. Ibrahim, K. Anson, F. Chinegwundoh, C. Corbishley, et al. “Clinical Presentation and Initial Management of Black Men and White Men with Prostate Cancer in the United Kingdom: The PROCESS Cohort Study.” British Journal of Cancer 102, no. 2 (January 19, 2010): 249–54. doi:10.1038/sj.bjc.6605461.
    • Vancouver/ICMJE:
      Evans S, Metcalfe C, Patel B, Ibrahim F, Anson K, Chinegwundoh F, et al. Clinical presentation and initial management of black men and white men with prostate cancer in the United Kingdom: the PROCESS cohort study. British Journal of Cancer [Internet]. 2010 Jan 19 [cited 2019 Oct 18];102(2):249–54. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=47602674&custid=s8280428