Bladder dysfunction and hypertension in children with Guillain-Barre syndrome.

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  • Additional Information
    • Subject Terms:
    • Author-Supplied Keywords:
      Autonomic dysfunction
      Child
      Guillain-Barre syndrome
      Hypertension
    • Abstract:
      Background: Guillain-Barre syndrome (GBS) causes acute motor, sensory and autonomic dysfunction. There is a relative paucity of published data regarding the autonomic features of GBS. The aims of this study were to describe the incidence, management and outcome of bladder dysfunction and hypertension in GBS and to ascertain whether these features relate to muscle weakness severity. Case-Diagnosis/Treatment: Twenty-seven patients with a median (interquartile range) age of 5.7 (3.5-8.4) years were included, of whom 18 (67 %) were male and 14 (52 %) had autonomic dysfunction. One patient presented with and three subsequently developed urinary retention necessitating catheterisation for a median of 7.5 (7-14.5) days. Univariate analysis demonstrated that urinary retention was associated with weakness in all four limbs [retention: MRC muscle grade 2 (2-2.75); no retention: MRC grade 4 (3-4); p = 0.02], possibly reflecting more severe disease. Patients with hypertension (12 patients, 44 %) had a longer hospital stay [median 32.5 (15.5-53.5) days; rho = 0.65; p = 0.02], and those with worse muscle weakness required more anti-hypertensive medications (upper limb rho = −0.71, p = 0.03; lower limb rho = −0.72, p = 0.03]. The majority of blood pressure treatments involved calcium channel and beta blockers. Conclusion: In children with GBS, bladder dysfunction and hypertension are common. The presence of severe muscle weakness may predict those at greatest risk of these complications. [ABSTRACT FROM AUTHOR]
    • Abstract:
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    • Author Affiliations:
      1Department of Paediatric Neurology, Royal Manchester Children's Hospital, Manchester UK
      2Department of Paediatric Nephrology, Royal Manchester Children's Hospital and Manchester Academic Health Science Centre, University of Manchester, Manchester UK
    • ISSN:
      0931-041X
    • Accession Number:
      10.1007/s00467-014-2799-2
    • Accession Number:
      97680198
  • Citations
    • ABNT:
      WATSON, L. et al. Bladder dysfunction and hypertension in children with Guillain-Barre syndromePediatric Nephrology. [s.l: s.n.]. Disponível em: . Acesso em: 17 set. 2019.
    • AMA:
      Watson L, Aziz M, Vassallo G, Plant N, Webb N. Bladder Dysfunction and Hypertension in Children with Guillain-Barre Syndrome. Vol 29.; 2014:1637-1641. doi:10.1007/s00467-014-2799-2.
    • APA:
      Watson, L., Aziz, M., Vassallo, G., Plant, N., & Webb, N. (2014). Bladder dysfunction and hypertension in children with Guillain-Barre syndrome. Pediatric Nephrology (Vol. 29, pp. 1637–1641). https://doi.org/10.1007/s00467-014-2799-2
    • Chicago/Turabian: Author-Date:
      Watson, Louise, Majid Aziz, Grace Vassallo, Nicholas Plant, and Nicholas Webb. 2014. “Bladder Dysfunction and Hypertension in Children with Guillain-Barre Syndrome.” Pediatric Nephrology. Vol. 29. doi:10.1007/s00467-014-2799-2.
    • Harvard:
      Watson, L. et al. (2014) Bladder dysfunction and hypertension in children with Guillain-Barre syndrome, Pediatric Nephrology, pp. 1637–1641. doi: 10.1007/s00467-014-2799-2.
    • Harvard: Australian:
      Watson, L, Aziz, M, Vassallo, G, Plant, N & Webb, N 2014, Bladder dysfunction and hypertension in children with Guillain-Barre syndrome, Pediatric Nephrology, September, vol 29, pp. 1637–1641, viewed 17 September 2019, .
    • MLA:
      Watson, Louise, et al. “Bladder Dysfunction and Hypertension in Children with Guillain-Barre Syndrome.” Pediatric Nephrology, vol. 29, no. 9, Sept. 2014, pp. 1637–1641. EBSCOhost, doi:10.1007/s00467-014-2799-2.
    • Chicago/Turabian: Humanities:
      Watson, Louise, Majid Aziz, Grace Vassallo, Nicholas Plant, and Nicholas Webb. “Bladder Dysfunction and Hypertension in Children with Guillain-Barre Syndrome.” Pediatric Nephrology. Vol. 29, September 2014. doi:10.1007/s00467-014-2799-2.
    • Vancouver/ICMJE:
      Watson L, Aziz M, Vassallo G, Plant N, Webb N. Bladder dysfunction and hypertension in children with Guillain-Barre syndrome [Internet]. Vol. 29, Pediatric Nephrology. 2014 Sep [cited 2019 Sep 17] p. 1637–41. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=97680198&custid=s8280428