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Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding

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  • Additional Information
    • Publication Information:
      BMC, 2001.
    • Publication Date:
      2001
    • Collection:
      LCC:Medicine (General)
    • Abstract:
      Abstract The Carotid Revascularization Endarterectomy versus Stenting Trial (CREST) is a prospective, randomized, multicenter clinical trial of carotid endarterectomy (CEA) versus carotid artery stenting (CAS) as prevention for stroke in patients with symptomatic stenosis greater than or equal to 50%. CREST is sponsored by the US National Institute of Neurological Disorders and Stroke (NINDS) of the US National Institutes of Health (NIH), with additional support by a device manufacturer, and will provide data to the US Food and Drug Administration (FDA) for evaluation of a stent device. Because of budget constraints for CREST, Health Care Financing Administration (HCFA) reimbursement for hospital costs incurred by CREST patients will be essential. The involvement of academic scientists, industry, and three separate government agencies (NIH, FDA, HCFA) has presented many challenges in conducting the trial. A review of the pathways followed to meet these challenges may be helpful to others seeking to facilitate sharing of the costs and burdens of conducting innovative clinical research.
    • File Description:
      electronic resource
    • ISSN:
      1468-6708
    • Relation:
      http://cvm.controlled-trials.com/content/2/4/160; https://doaj.org/toc/1468-6708
    • Accession Number:
      10.1186/cvm-2-4-160
    • Rights:
      Journal Licence: CC BY
    • Accession Number:
      edsdoj.3fc653974032499c8e44ab74d08dce3e
  • Citations
    • ABNT:
      BROTT THOMAS G et al. Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding. Current Controlled Trials in Cardiovascular Medicine, [s. l.], v. 2, n. 4, p. 160–164, 2001. DOI 10.1186/cvm-2-4-160. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsdoj&AN=edsdoj.3fc653974032499c8e44ab74d08dce3e&custid=s8280428. Acesso em: 9 ago. 2020.
    • AMA:
      Brott Thomas G, Howard George, Howard Virginia J, Hobson Robert W, Roubin Gary S, Ferguson Robert DG. Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding. Current Controlled Trials in Cardiovascular Medicine. 2001;2(4):160-164. doi:10.1186/cvm-2-4-160
    • APA:
      Brott Thomas G, Howard George, Howard Virginia J, Hobson Robert W, Roubin Gary S, & Ferguson Robert DG. (2001). Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding. Current Controlled Trials in Cardiovascular Medicine, 2(4), 160–164. https://doi.org/10.1186/cvm-2-4-160
    • Chicago/Turabian: Author-Date:
      Brott Thomas G, Howard George, Howard Virginia J, Hobson Robert W, Roubin Gary S, and Ferguson Robert DG. 2001. “Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and Industry Funding.” Current Controlled Trials in Cardiovascular Medicine 2 (4): 160–64. doi:10.1186/cvm-2-4-160.
    • Harvard:
      Brott Thomas G et al. (2001) ‘Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding’, Current Controlled Trials in Cardiovascular Medicine, 2(4), pp. 160–164. doi: 10.1186/cvm-2-4-160.
    • Harvard: Australian:
      Brott Thomas G, Howard George, Howard Virginia J, Hobson Robert W, Roubin Gary S & Ferguson Robert DG 2001, ‘Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding’, Current Controlled Trials in Cardiovascular Medicine, vol. 2, no. 4, pp. 160–164, viewed 9 August 2020, .
    • MLA:
      Brott Thomas G, et al. “Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and Industry Funding.” Current Controlled Trials in Cardiovascular Medicine, vol. 2, no. 4, July 2001, pp. 160–164. EBSCOhost, doi:10.1186/cvm-2-4-160.
    • Chicago/Turabian: Humanities:
      Brott Thomas G, Howard George, Howard Virginia J, Hobson Robert W, Roubin Gary S, and Ferguson Robert DG. “Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and Industry Funding.” Current Controlled Trials in Cardiovascular Medicine 2, no. 4 (July 1, 2001): 160–64. doi:10.1186/cvm-2-4-160.
    • Vancouver/ICMJE:
      Brott Thomas G, Howard George, Howard Virginia J, Hobson Robert W, Roubin Gary S, Ferguson Robert DG. Organizing the Carotid Revascularization Endarterectomy versus Stenting Trial (CREST): National Institutes of Health, Health Care Financing Administration, and industry funding. Current Controlled Trials in Cardiovascular Medicine [Internet]. 2001 Jul 1 [cited 2020 Aug 9];2(4):160–4. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edsdoj&AN=edsdoj.3fc653974032499c8e44ab74d08dce3e&custid=s8280428