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Hypnosis and communication reduce pain and anxiety in peripheral intravenous cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a multicentre randomised trial

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  • Additional Information
    • Affiliation:
      1 Anesthesia and Intensive Care Department, Centre Hospitalier Universitaire de Rennes, Université de Rennes, Inserm CIC 1414 Numecan, Rennes, France
      2 Émergences Campus, Hypnosis Institute, Rennes, France
      3 Anesthesia Department, Centre Hospitalier privé Saint Grégoire, Saint Grégoire, France
      4 Anesthesiology Department, Cliniques universitaires Saint-Luc, Université catholique de Louvain, Brussels, Belgium
      5 Clinical Pharmacology Department, Centre Hospitalier Universitaire de Rennes, Université de Rennes, Inserm, Rennes, France
    • Note:
      Handling editor: Hugh C Hemmings Jr
    • Keywords:
      anaesthesia
      anxiety
      hypnosis
      pain
      patient experience
      peripheral intravenous cannulation
    • Abstract:
      Background Clinicians traditionally warn patients of pain before peripheral i.v. cannulation (PIVC). However, using words related to pain or undesirable experiences can result in greater pain and anxiety. The use of positive words can improve pain perception and subjective patient experience. We aimed to compare the effects of three types of communication, including hypnotic communication, on pain, comfort, and anxiety in patients during PIVC.
    • Abstract:
      Results Of the 272 subjects analysed (hypnosis, n=89; nocebo, n=92; neutral, n=91), pain after PIVC was lower in the hypnosis group (mean [standard deviation]; range) (1.5 [1.9]; 0–5) compared with the neutral (3.5 [2.3]; 0–9; P<0.0001) and nocebo groups (3.8 [2.5]; 0–10; P<0.0001). Whilst anxiety was higher and comfort lower before PIVC in the hypnosis group, anxiety decreased and comfort perception increased after PIVC when hypnosis was used.
    • Abstract:
      Conclusions This is one of the first well-designed RCTs showing a significant benefit of a hypnosis technique during a routine procedure, such as PIVC. The results could facilitate implementation of hypnosis in daily clinical care.
    • Abstract:
      Clinical trial registration NCT02662322.
    • ISSN:
      0007-0912
    • Accession Number:
      10.1016/j.bja.2019.11.020
    • Accession Number:
      S000709121930892X
    • Copyright:
      © 2019 British Journal of Anaesthesia. Published by Elsevier Ltd. All rights reserved.
  • Citations
    • ABNT:
      AHMIN, M. et al. Hypnosis and communication reduce pain and anxiety in peripheral intravenous cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a multicentre randomised trial. British Journal of Anaesthesia, [s. l.], v. 124, n. 3, p. 292–298, 2020. DOI 10.1016/j.bja.2019.11.020. Disponível em: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edselp&AN=S000709121930892X&custid=s8280428. Acesso em: 30 out. 2020.
    • AMA:
      Ahmin M, Barthes S, Boulon N, et al. Hypnosis and communication reduce pain and anxiety in peripheral intravenous cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a multicentre randomised trial. British Journal of Anaesthesia. 2020;124(3):292-298. doi:10.1016/j.bja.2019.11.020
    • APA:
      Ahmin, M., Barthes, S., Boulon, N., Branchu, P., Copin-Eliat, C., Delahaye-Larralde, S., Fillatre, P., Donal, C., Hugot, P., Gauvrit, C., Guillou, N., Leroyer, I., Pouliquen, C., Renault, A., Rolland, E., Rousseau, C., Rullier, J., Schonne, S., Yven, T., … Beloeil, H. (2020). Hypnosis and communication reduce pain and anxiety in peripheral intravenous cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a multicentre randomised trial. British Journal of Anaesthesia, 124(3), 292–298. https://doi.org/10.1016/j.bja.2019.11.020
    • Chicago/Turabian: Author-Date:
      Ahmin, Mustapha, Sébastien Barthes, Natacha Boulon, Patricia Branchu, Catherine Copin-Eliat, Séverine Delahaye-Larralde, Pierre Fillatre, et al. 2020. “Hypnosis and Communication Reduce Pain and Anxiety in Peripheral Intravenous Cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a Multicentre Randomised Trial.” British Journal of Anaesthesia 124 (3): 292–98. doi:10.1016/j.bja.2019.11.020.
    • Harvard:
      Ahmin, M. et al. (2020) ‘Hypnosis and communication reduce pain and anxiety in peripheral intravenous cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a multicentre randomised trial’, British Journal of Anaesthesia, 124(3), pp. 292–298. doi: 10.1016/j.bja.2019.11.020.
    • Harvard: Australian:
      Ahmin, M, Barthes, S, Boulon, N, Branchu, P, Copin-Eliat, C, Delahaye-Larralde, S, Fillatre, P, Donal, C, Hugot, P, Gauvrit, C, Guillou, N, Leroyer, I, Pouliquen, C, Renault, A, Rolland, E, Rousseau, C, Rullier, J, Schonne, S, Yven, T, Fusco, N, Bernard, F, Roelants, F, Watremez, C, Musellec, H, Laviolle, B & Beloeil, H 2020, ‘Hypnosis and communication reduce pain and anxiety in peripheral intravenous cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a multicentre randomised trial’, British Journal of Anaesthesia, vol. 124, no. 3, pp. 292–298, viewed 30 October 2020, .
    • MLA:
      Ahmin, Mustapha, et al. “Hypnosis and Communication Reduce Pain and Anxiety in Peripheral Intravenous Cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a Multicentre Randomised Trial.” British Journal of Anaesthesia, vol. 124, no. 3, Mar. 2020, pp. 292–298. EBSCOhost, doi:10.1016/j.bja.2019.11.020.
    • Chicago/Turabian: Humanities:
      Ahmin, Mustapha, Sébastien Barthes, Natacha Boulon, Patricia Branchu, Catherine Copin-Eliat, Séverine Delahaye-Larralde, Pierre Fillatre, et al. “Hypnosis and Communication Reduce Pain and Anxiety in Peripheral Intravenous Cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a Multicentre Randomised Trial.” British Journal of Anaesthesia 124, no. 3 (March 1, 2020): 292–98. doi:10.1016/j.bja.2019.11.020.
    • Vancouver/ICMJE:
      Ahmin M, Barthes S, Boulon N, Branchu P, Copin-Eliat C, Delahaye-Larralde S, et al. Hypnosis and communication reduce pain and anxiety in peripheral intravenous cannulation: Effect of Language and Confusion on Pain During Peripheral Intravenous Catheterization (KTHYPE), a multicentre randomised trial. British Journal of Anaesthesia [Internet]. 2020 Mar 1 [cited 2020 Oct 30];124(3):292–8. Available from: http://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=edselp&AN=S000709121930892X&custid=s8280428