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  • 1-10 of  4,410 results for ""TRINUCLEOTIDE repeats""
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Academic Journal

Dynamics of strand slippage in DNA hairpins formed by CAG repeats: roles of sequence parity and trinucleotide interrupts.

  • Authors : Xu P; Department of Physics, North Carolina State University, Raleigh, NC 27695-8202, USA.; Pan F

Subjects: Inverted Repeat Sequences* ; Trinucleotide Repeats*; DNA/DNA/DNA/*chemistry

  • Source: Nucleic acids research [Nucleic Acids Res] 2020 Mar 18; Vol. 48 (5), pp. 2232-2245.Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Large-scale contractions of Friedreich's ataxia GAA repeats in yeast occur during DNA replication due to their triplex-forming ability.

Subjects: DNA Replication* ; Trinucleotide Repeats*; Friedreich Ataxia/Friedreich Ataxia/Friedreich Ataxia/*genetics

  • Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Jan 21; Vol. 117 (3), pp. 1628-1637. Date of Electronic Publication: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

Recovery in the Myogenic Program of Congenital Myotonic Dystrophy Myoblasts after Excision of the Expanded (CTG) n Repeat.

  • Authors : André LM; Department of Cell Biology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands.; van Cruchten RTP

Subjects: Trinucleotide Repeats*; Myoblasts/Myoblasts/Myoblasts/*pathology ; Myotonic Dystrophy/Myotonic Dystrophy/Myotonic Dystrophy/*genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2019 Nov 13; Vol. 20 (22). Date of Electronic Publication: 2019 Nov 13.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Recent advances in molecular therapies for neurological disease: triplet repeat disorders.

  • Authors : Gonzalez-Alegre P; Department of Neurology, the University of Pennsylvania, Philadelphia, PA 19104, USA.; Raymond G. Perelman Center for Cellular and Molecular Therapy, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

Subjects: Genetic Therapy*/Genetic Therapy*/Genetic Therapy*/methods ; Molecular Targeted Therapy* ; Trinucleotide Repeat Expansion*

  • Source: Human molecular genetics [Hum Mol Genet] 2019 Oct 01; Vol. 28 (R1), pp. R80-R87.Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN:

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Academic Journal

Ratiometric electrochemical biosensor based on Exo III-Assisted recycling amplification for the detection of CAG trinucleotide repeats.

  • Authors : Liu Y; Hubei Collaborative Innovation Center for Advanced Organic Chemical Materials & Ministry of Education Key Laboratory for the Synthesis and Application of Organic Functional Molecules, Hubei University, Youyi Road 368, Wuchang, Wuhan, Hubei, 430062, PR China.; Ge Z

Subjects: Trinucleotide Repeats*; Biosensing Techniques/Biosensing Techniques/Biosensing Techniques/*methods ; DNA Probes/DNA Probes/DNA Probes/*chemistry

  • Source: Biosensors & bioelectronics [Biosens Bioelectron] 2019 Oct 01; Vol. 142, pp. 111537. Date of Electronic Publication: 2019 Jul 25.Publisher: Elsevier Advanced Technology Country of Publication: England NLM ID: 9001289 Publication Model: Print-Electronic Cited Medium: Internet

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Academic Journal

C9orf72 and triplet repeat disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms.

  • Authors : Wang X; Department of Biochemistry, University of Colorado Boulder, Boulder, Colorado 80309, USA.; BioFrontiers Institute and Howard Hughes Medical Institute, University of Colorado Boulder, Boulder, Colorado 80309, USA.

Subjects: Trinucleotide Repeats*; Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/Amyotrophic Lateral Sclerosis/*genetics ; C9orf72 Protein/C9orf72 Protein/C9orf72 Protein/*chemistry Frontotemporal Dementia With Motor Neuron Disease

  • Source: RNA (New York, N.Y.) [RNA] 2019 Aug; Vol. 25 (8), pp. 935-947. Date of Electronic Publication: 2019 May 02.Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 9509184 Publication Model: Print-Electronic Cited Medium:

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Academic Journal

p53 Binds Preferentially to Non-B DNA Structures Formed by the Pyrimidine-Rich Strands of GAA·TTC Trinucleotide Repeats Associated with Friedreich's Ataxia.

  • Authors : Helma R; Institute of Biophysics, Academy of Sciences of the Czech Republic v.v.i., Královopolská 135, 612 65 Brno, Czech Republic. .; Department of Molecular Biology and Pharmaceutical Biotechnology, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Palackého 1/3, 612 42 Brno, Czech Republic. .

Subjects: Nucleic Acid Conformation* ; Trinucleotide Repeat Expansion* ; Trinucleotide Repeats*

  • Source: Molecules (Basel, Switzerland) [Molecules] 2019 May 31; Vol. 24 (11). Date of Electronic Publication: 2019 May 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049

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Academic Journal

The prevalence of CGG repeat expansion mutation in FMR1 gene in the northern Chinese women of reproductive age.

  • Authors : Ma Y; Department of Central Laboratory, Peking University First Hospital, Beijing, 100034, China.; Wei X

Subjects: Mutation* ; Reproduction* ; Trinucleotide Repeats*

  • Source: BMC medical genetics [BMC Med Genet] 2019 May 16; Vol. 20 (1), pp. 81. Date of Electronic Publication: 2019 May 16.Publisher: BioMed Central Country of Publication: England NLM ID: 100968552 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2350

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Academic Journal

Analysis of mutational dynamics at the DMPK (CTG)n locus identifies saliva as a suitable DNA sample source for genetic analysis in myotonic dystrophy type 1.

  • Authors : Corrales E; Instituto de Investigaciones en Salud (INISA), Universidad de Costa Rica, San José, Costa Rica.; Vásquez M

Subjects: Genetic Loci* ; Myotonic Dystrophy*/Myotonic Dystrophy*/Myotonic Dystrophy*/diagnosis ; Myotonic Dystrophy*/Myotonic Dystrophy*/Myotonic Dystrophy*/genetics

  • Source: PloS one [PLoS One] 2019 May 02; Vol. 14 (5), pp. e0216407. Date of Electronic Publication: 2019 May 02 (Print Publication: 2019).Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet

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Academic Journal

Repeat expansion scanning of the NOTCH2NLC gene in patients with multiple system atrophy.

Subjects: *MULTIPLE system atrophy; *TRINUCLEOTIDE repeats; *SWEAT glands

  • Source: Annals of Clinical & Translational Neurology. Apr2020, Vol. 7 Issue 4, p517-526. 10p.

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  • 1-10 of  4,410 results for ""TRINUCLEOTIDE repeats""